Delivery devices, systems and methods for delivering therapeutic agents
AssigneesCell Precision, LLC, Emory University
InventorsMichael L. Wach, Raymond P. Vito, W. Robert Taylor, Jack Griffis
Life of this patent
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Abstract
Delivery devices, systems, and methods are configured to increase the retention of the therapeutic agent, and thereby increase the dose of the agent delivered. The delivery device may include a delivery body and a retractable member configured to move with respect to the delivery body. The retractable member may include a puncture member configured to create a delivery channel at the treatment site. The body may include an opening through which an agent may be delivered after the retractable member has been retracted within the device.
Claims20
A device for delivering an agent to a treatment site, comprising:
- a body having a first end, an opposing second end and a length between the first end and the second end, the body including a channel between the first end and a second end, the channel including at least one opening configured to deliver the agent, the body including a first section and a second section, a diameter of the first section being larger than a diameter of the second section, a portion of the second section being parallel with the first section, the diameter of the inner channel corresponding to the diameter of the body;
- and
- a retractable member having a first end, an opposing second end, and a length between the first end and the second end, the retractable member including at least one puncture member configured to penetrate tissue to create a delivery channel at the treatment site, the at least one puncture member being disposed at the second end, the retractable member being configured to move relative to the body;
- wherein the retractable member is configured to move with respect to the body;
- and
- wherein the body is configured to deliver the agent when the retractable member including the puncture member is retracted within the body.
A device for delivering an agent to a treatment site, comprising:
- a body having a first end, an opposing second end and a length between the first end and the second end, the body including a channel between the first end and a second end, the channel including at least one opening configured to deliver the agent, the body including a first section and a second section, the second section including a first portion and a second portion, a diameter of the first section being larger than a diameter of the second section, the second portion being parallel with the first section, the diameter of the inner channel corresponding to the diameter of the body;
- and
- a retractable member having a first end, an opposing second end, and a length between the first end and the second end, the retractable member including a first puncture member configured to penetrate tissue to create a delivery channel at the treatment site, the first puncture member being disposed at the second end, the retractable member being configured to move relative to the body;
- wherein the retractable member is configured to move between at least a first position and a second position, the first position corresponding to when a portion of the retractable member is disposed within the channel, the second position corresponding to when at least the portion of the retractable member is retracted within the body, and
- wherein the body is configured to deliver the agent when the retractable member is disposed at the second position.
Dependencies are inferred from the claim text.