Systems and methods for intra-operative stimulation

A hand-held tissue stimulation system comprising:

• a housing;
• a stimulation control device comprising stimulation signal generating circuitry for generation of an electrical stimulation signal having an amplitude and a duration, a microcontroller electrically coupled to the stimulation signal generating circuitry, and a source of power for the stimulation control device;
• a probe configured for contact with a targeted tissue region, the probe extending from the housing;
• a return electrode electrically coupled to the signal generating circuitry and configured to provide an electrical flow path for the stimulation signal from the probe back to the stimulation control device;
• an indicator carried on the housing and electrically coupled to the microcontroller for confirming status conditions during use of the system, wherein the indicator is configured to display two or more different signals to indicate different conditions.