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AssigneeEcole Polytechnique Federale De Lausanne (Epfl)
InventorsTheo LASSER, Marc Andre, Michael Friedrich
Estimating the term…
A high-speed laser perfusion imaging instrument including a laser source, a detector, a signal-processing unit, data memory, and a screen to display results. A section of a sample surface is illuminated with laser light; reemitted light from the irradiated surface is collected by focusing optics on a 2D array of integrating photodetectors having elements that can be accessed individually or in a pre-defined selection of pixels at high speed. This 2D array measures intensity variations at each individual pixel. Average amplitude and mean frequency of the measured signal contain information about concentration and speed of moving blood cells. For real-time imaging, exposure time is used as a parameter to measure relative perfusion changes. These data are stored and processed with the signal-processing unit to deliver 2D flow maps of the illuminated sample section, and allow a simple overlay between a conventional image and processed flow maps.
A Laser Perfusion Imaging system comprising:
A Laser Perfusion Imaging system according to any of the pervious claims further comprising a processing unit which uses the detected laser Doppler signal to adjust the Laser speckle signal.
A Laser Perfusion Imaging system according to any of the previous claims further comprising a processing unit which calculates perfusion map and/or reliability map from a combination of LDI and LSI maps of the same observed object.
A method to adjust laser speckle maps based on laser Doppler signals, comprising:
A method to combine laser speckle and laser Doppler maps, comprising:
Dependencies are inferred from the claim text.