Non-invasive or minimally invasive paraspinal sympathetic ablation for the treatment of resistant hypertension
AssigneeEnigma Medical, Inc.
InventorsDenise Barbut, Allan Rozenberg, Axel Heinimann
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Abstract
A method of ablating the sympathetic ganglionic cell bodies in the thoracic paravertebral space is provided. The method includes ablating the sympathetic ganglionic cell bodies in the thoracic paravertebral space through a posterior, non-invasive or minimally invasive approach for the treatment of resistant hypertension. The ablation may additionally involve various permutations of the gray and white rami and the dorsal root ganglion in addition to the sympathetic chain ganglionic cell bodies, all located in the triangular paravertebral space.
Claims42
A method comprising reducing blood pressure of a patient by percutaneously accessing para-vertebral sympathetic ganglia, dorsal root ganglia or both;
- and irreversibly disabling said ganglia.
A method comprising reducing blood pressure of a patient by accessing a para-vertebral triangle;
- and irreversibly disabling neural structures therewithin.
A method comprising treating heart failure, acute myocardial infarction, renal disease, or chronic renal failure by percutaneously accessing para-vertebral sympathetic ganglia, dorsal root ganglia or both;
- and irreversibly disabling said ganglia.
A method comprising stimulating para-vertebral sympathetic ganglia, dorsal root ganglia or both of a patient;
- monitoring a physiologic response related to said stimulating;
- applying ablative means to said para-vertebral sympathetic ganglia, dorsal root ganglia or both;
- and reducing blood pressure of said patient.
A method comprising stimulating a para-vertebral triangle;
- monitoring a physiologic response related to said stimulating;
- applying ablative means to said para-vertebral triangle.
A device for reducing blood pressure, comprising an elongate tubular member with a proximal and distal end, adapted for percutaneous insertion proximate or within the para-vertebral sympathetic ganglia or dorsal root ganglia.
Dependencies are inferred from the claim text.