Formulations and methods for treating amyloidosis

A method of stabilizing or improving renal and/or gastrointestinal function in a subject in need thereof, said method comprising:

• administering to said subject a therapeutically effective amount of a compound selected from the group consisting of:
• 1,2-ethanedisulfonic acid,
• sodium 1,2-ethanedisulfonate,
• 1.2-ethanediol bis(hydrogen sulfate),
• 1,2-ethanediol disulfate, disodium salt,
• 1,3-propanedisulfonic acid,
• sodium 1,3-propanedisulfonate (1,3-propanedisulfonic acid, disodium salt),
• 1,3-propanediol bis(hydrogen sulfate),
• 1,3-propanediol disulfate, disodium salt,
• 2-sulfomethyl-1,4-butanedisulfonic acid, and
• 2-sulfomethylbutane-1,4-disulfonic acid, trisodium salt.

A method of treating a malignant neoplasm in a subject in need thereof, said method comprising:

• administering to said subject a therapeutically effective amount of a compound selected from the group consisting of:
• 1,2-ethanedisulfonic acid,
• sodium 1,2-ethanedisulfonate,
• 1,2-ethanediol bis(hydrogen sulfate),
• 1,2-ethanediol disulfate, disodium salt,
• 1,3-propanedisulfonic acid,
• sodium 1,3-propanedisulfonate (1,3-propanedisulfonic acid, disodium salt),
• 1,3-propanediol bis(hydrogen sulfate),
• 1,3-propanediol disulfate, disodium salt,
• 2-sulfomethyl-1,4-butanedisulfonic acid, and
• 2-sulfomethylbutane-1,4-disulfonic acid, trisodium salt,
• in combination with a second agent such that the malignant neoplasm is treated in said subject.

A method of treating a chronic infection in a subject in need thereof, said method comprising:

• administering to said subject a therapeutically effective amount of a compound selected from the group consisting of:
• 1,2-ethanedisulfonic acid,
• sodium 1,2-ethanedisulfonate,
• 1,2-ethanediol bis(hydrogen sulfate),
• 1,2-ethanediol disulfate, disodium salt,
• 1,3-propanedisulfonic acid,
• sodium 1,3-propanedisulfonate (1,3-propanedisulfonic acid, disodium salt),
• 1,3-propanediol bis(hydrogen sulfate),
• 1,3-propanediol disulfate, disodium salt,
• 2-sulfomethyl-1,4-butanedisulfonic acid, and
• 2-sulfomethylbutane-1,4-disulfonic acid, trisodium salt,
• in combination with a second agent such that the chronic infection is treated in said subject.