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US 2013/0296430 A1Published application
Compositions and methods for treating autism and autism spectrum disorder
OwnerAntonio Hardan, Rabin Tirouvanziam +1inventors
InventorsAntonio Hardan, Rabin Tirouvanziam, Leonora A. Herzenberg
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Abstract
The described invention provides a method for treating a behavioral deficit, such as irritability and stereotypic/repetitive behaviors, in a subject with autism spectrum disorder by administering a composition comprising a therapeutic amount of N-acetylcysteine, a derivative of N-acetylcysteine, or a pharmaceutically acceptable salt of N-acetylcysteine.
Claims27
A method for treating a behavioral deficit in a subject with autism spectrum disorder characterized by glutamatergic dysfunction and redox imbalance, the method comprising:
- (a) administering to the subject a pharmaceutical composition comprising a therapeutic amount of N-acetylcysteine, a derivative of N-acetylcysteine, or a pharmaceutically acceptable salt of N-acetylcysteine, wherein the therapeutic amount is from about 900 mg per day to about 2,700 mg per day, and wherein the therapeutic amount is effective to treat the behavioral deficit in the subject.
Dependencies are inferred from the claim text.