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US 2013/0296402 A1Published application
Base modified oligonucleotides
AssigneeMiragen Therapeutics, Inc.
InventorsKurt Vagle, Christina Dalby, William S. Marshall
Life of this patent
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Abstract
The present invention relates to oligonucleotides with base modified nucleosides for enhancement of binding affinity.
Claims32
An oligonucleotide comprising at least one nucleotide having a 2′ modification and at least one nucleotide having an amino carbonyl modified base.
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