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US 2013/0296400 A1Published application
Antidotes to antisense compounds
AssigneeIsis Pharmaceuticals, Inc.
InventorsBrett P. Monia, Andrew M. Siwkowski, Hong Zhang
Life of this patent
Estimating the term…
Abstract
The present invention relates to antisense antidote compounds and uses thereof. Such antidote compounds reduce the magnitude and/or duration of the antisense activity of an antisense compound.
Claims29
An antidote compound comprising a modified oligonucleotide consisting of 12 to 30 linked nucleosides and having a nucleobase sequence complementary to an antisense compound.
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18-25. (canceled)
33-59. (canceled)
A kit comprising an antisense compound and an antidote compound.
A kit comprising an antidote compound and a non-oligomeric antidote.
Dependencies are inferred from the claim text.