3-spirocyclic piperidine derivatives as ghrelin receptor agonists
OwnerAmeet Vijay Ambarkhaneinventor
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Abstract
The invention relates to derivatives of formula (I), wherein the substituents are as defined in the specification; to processes for the preparation of such derivatives; pharmaceutical compositions comprising such derivatives; such derivatives as a medicament; such derivatives for the treatment of a disorder or a disease mediated by the ghrelin receptor.
Claims36
A compound which is 2-Amino-N—[(R)-1-benzyloxymethyl-2-((4S,5R)-2-methyl-1-oxo-4-phenyl-2,7-diaza-spiro[4.5]dec-7-yl)-2-oxo-ethyl]-2-methyl-propionamide L-malate salt.
A compound which is 2-amino-N-((2R)-3-(benzyloxy)-1-(2-methyl-1-oxo-4-p-tolyl-2,7-diazaspiro[4.5]decan-7-yl)-1-oxopropan-2-yl)-2-methylpropanamide L-malate salt.
A compound which is 2-Amino-N-{(R)-1-benzyloxymethyl-2-[(4S,5R)-4-fluoro-phenyl)-2-methyl-1-oxo-2,7-diaza-spiro[4,5]dec-7-yl]-2-oxoethyl}2-methylpropionamide L-malate salt.
Dependencies are inferred from the claim text.