2-Carboxamide-7-Piperazinyl-Benzofuran Derivatives

A compound of formula (I),

• wherein
• R1 is heteroaryl or heterocyclyl, wherein said heteroaryl or heterocyclyl is optionally substituted with one or more substituents selected from C1-4alkyl, halogen, CF3, CN, C1-4alkoxy, C(O)C1-4alkyl, NC1-4alkylC(O)C1-4alkyl, NHC(O)C1-4alkyl, C(O)HN(C1-4alkyl) and C(O)N(C1-4alkyl)2;
• R2 is C1-4alkyl, heterocyclyl, C1-4alkylaryl, C1-4alkylheteroaryl, carbocyclyl, C1-4alkylheterocyclyl, heterocyclyl-heteroaryl, aryl-heterocyclyl, carbocyclyl-heteroaryl, heterocyclyl-aryl, wherein in said groups the heterocyclyl, aryl, heteroaryl or carbocyclyl moiety may be optionally substituted with one or more substituents selected from halogen, C1-4alkoxy, C(O)C1-4alkyl, C0-4alkylSO2C1-4alkyl, cyano, hydroxy, and C1-4alkyl;
• R3 is hydrogen or C1-4alkyl, or
• R2 and R3 may together with the nitrogen atom, form a saturated ring system containing 4, 5 or 6 ring forming atoms selected from carbon or nitrogen and wherein said ring system is optionally substituted with one or more substituent selected from halogen, C1-4alkyl and C1-4alkoxy, O-heteroaryl;
• R4 is hydrogen, halogen, methyl or methoxy;
• or a pharmaceutically acceptable salt thereof.