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US 2013/0296291 A1Published application
1,3,4-oxadiazole and 1,3,4-thiadiazole beta-lactamase inhibitors
AssigneeCubist Pharmaceuticals, Inc.
InventorsYu Gui Gu, Yong He, Ning Yin, Dylan C. Alexander, Jason B. Cross, Chester A. Metcalf, III, Robert Busch
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Abstract
β-Lactamase inhibitor compounds (BLIs) are disclosed, including compounds that have activity against class A, class C or class D β-lactamases. Methods of manufacturing the BLIs, and uses of the compounds in the preparation of pharmaceutical compositions and antibacterial applications are also disclosed.
Claims21
A compound of the formula:
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.