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AssigneeDermal Research Laboratories, Inc.
InventorsHarold G. Brown, Carol A. Cooper, Kristina J. Hennessy, Karen K. Brown
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The invention discloses the discovery that a pharmaceutical composition containing complex carbohydrates with or without natural or synthetic essential oils can work effectively as a topical, oral or mucosal pharmaceutical composition. Such pharmaceutical compositions reduce inflammation, assist in wound healing, protect against bruising, relieve itching, relieve pain and swelling and treat topical bacterial infections such as acne and decubitus ulcers and prevent and treat numerous other conditions and diseases. Such pharmaceutical compositions can be administered to mammals including humans. Also included in this invention are methods to deliver topically applied macromolecules into the tissue of mammals and methods of blocking the adhesion, metastatic and coronary cascades.
A composition which comprises an effective amount of at least one orally ingestable or mucosally absorbable low purity hyaluronic acid or salt thereof, comprising at least one fraction having a molecular weight in the range of greater than 1,000,000 daltons, as measured using a protein standard/intrinsic viscosity, with the proviso that said composition does not contain an essential oil as an active ingredient, and wherein the low purity hyaluronic acid or salt thereof contains up to 5% by weight protein contaminants and is not a pharmaceutical grade.
An orally ingestible or mucosally absorbable composition selected from the group consisting of a drink, a drink mix, food, candy, mouthwash, toothpaste, gargle, vaporizer, gum, lozenge, ingestable gel, ingestable foam, ingestable capsule, tablet, ingestable tablet, ingestable dissolvable tablet, suppository, and ingestable nutritional supplement, which comprises an effective amount of at least one low purity hyaluronic acid or salt thereof wherein said at least one low purity hyaluronic acid or salt thereof comprises at least one fraction having a molecular weight range greater than 1,000,000 daltons as measured using a protein standard/intrinsic viscosity, said composition does not contain an essential oil as an active ingredient, and wherein the low purity hyaluronic acid or salt is not a pharmaceutical grade.
A nutritional supplement comprising an nutritionally effective amount of at least one orally ingestable or mucosally absorbable low purity hyaluronic acid or salt thereof, comprising at least one fraction having a molecular weight in the range of greater than 1,000,000 daltons, as measured using a protein standard/intrinsic viscosity, with the proviso that said composition does not contain an essential oil as an active ingredient, and wherein the low purity hyaluronic acid or salt thereof contains up to 5% by weight protein contaminants, and a food or drink carrier, the nutritional supplement provided in an orally ingestible dosage form, wherein the hyaluronic acid or a salt thereof is present in an amount of between 0.01% and 5.0 wt/vol., wherein said low purity hyaluronic acid is defined as not causing reactions when applied to the skin of mammals or when delivered orally or mucosally to mammals and wherein the low purity hyaluronic acid or salt is not a pharmaceutical grade.
A nutritional supplement comprising an effective amount of an orally ingestible or orally absorbable low purity hyaluronic acid or salts thereof wherein the hyaluronic acid contains at least one fraction having a molecular weight of greater than 1,000,000 daltons, as measured using a protein standard/intrinsic viscosity with the proviso that said composition does not contain an essential oil as an active ingredient, and wherein the low purity hyaluronic acid or salt is not a pharmaceutical grade.
Dependencies are inferred from the claim text.