Material for Wound Healing and Skin Reconstruction
Assignee3-D Matrix, Ltd.
InventorsKentaro Takamura, Jiro Takei
Life of this patent
Estimating the term…
Abstract
The invention relates to a material for wound healing and skin reconstruction containing a peptide, wherein the peptide is a self-assembling peptide which is an amphiphilic peptide having 8 to 200 amino acid residues with periodic repeats of alternating hydrophilic amino acids and hydrophobic amino acids, and forms a stable β-sheet structure in an aqueous solution in the presence of a monovalent ion. The material for wound healing and skin reconstruction of the present invention is capable of healing a wound area of mammals quicker than spontaneous recovery without leaving any scars, wherein the material has no potential risk of infectious disease such as virus transmission.
Claims8
A method for wound healing and skin reconstruction, comprising the step of applying to an area of skin in need thereof a peptide, wherein said peptide is a self-assembling peptide which is an amphiphilic peptide having 8 to 200 amino acid residues with periodic repeats of alternating amino acids of arginine, alanine, aspartic acid and alanine, and said peptide adopts a stable β-sheet structure in an aqueous solution in the presence of a monovalent ion.
(canceled)
(canceled)
A method of sealing a wound in a patient, comprising the step of:
- (a) applying an effective amount of a self-assembling peptide to a wound of a patient, wherein said peptide is an amphiphilic peptide having 8 to 200 amino acid residues with periodic repeats of alternating amino acids of arginine, alanine, aspartic acid and alanine, and said peptide adopts a stable β-sheet structure in an aqueous solution in the presence of a monovalent ion.
Dependencies are inferred from the claim text.