US 2013/0296174 A1 · Microfluidics System for Sequencing

Abstract

A microfluidic chip (100) for use in multiplexed analysis of samples is described. The microfluidic chip (100) comprises a plurality of sensing chambers (130) and further comprises at least a first fluid supply channel (110) for providing a first fluid and a plurality of microfluidic channels (120). These are in fluid communication with at least one sensing chamber (130) and with the first fluid supply channel (110) for delivery of said first fluid to the at least one sensing chamber. The microfluidic channels (120) are branching off from the supply channel (110) in the neighbourhood of the sensing chamber (130) that can be provided with the first fluid through the microfluidic channel (120). The different channels (110, 120) thus form a tree-like delivery distribution system for supplying the first fluid to said plurality of sensing chambers (130).

Claims13

Dependent claims

A microfluidic chip for use in multiplexed analysis of samples, the microfluidic chip comprising a plurality of sensing chambers and the microfluidic chip further comprising

at least a first fluid supply channel for providing a first fluid,
a plurality of microfluidic channels, each microfluidic channel being in fluid communication with at least one sensing chamber, whereby each of the microfluidic channels is in fluid communication with said first fluid supply channel for delivery of said first fluid from said supply channel to said at least one sensing chamber, the microfluidic channels branching off from the supply channel in the neighbourhood of the sensing chamber that can be provided with the first fluid through the microfluidic channel, the different channels thus forming a tree-like delivery distribution system for supplying the first fluid to said plurality of sensing chambers.

A method for performing multiplexed analysis of samples based on microfluidics, the method comprising

delivery of at least one fluid from a common supply channel, through a plurality of microfluidic channels towards the plurality of sensing chambers, whereby each microfluidic channel transports the fluid from the common supply channel to a sensing chamber and each of the microfluidic channels branches off in the neighbourhood of the measurement site it can deliver fluid to, the channels thus forming a tree-like delivery distribution system for supplying the first fluid to said plurality of sensing chambers, and
sensing an interaction between a component in the sensing site and a component delivered with the fluid.

Dependencies are inferred from the claim text.

Microfluidics System for Sequencing

Life of this patent

Microfluidics System for Sequencing

Life of this patent

Abstract

Claims13