Conjugated polymers for use in homogeneous and solid state assays
AssigneeThe Regents of the University of California
InventorsGuillermo C. BAZAN, Bin LIU
Life of this patent
Estimating the term…
Loading patent…
AssigneeThe Regents of the University of California
InventorsGuillermo C. BAZAN, Bin LIU
Estimating the term…
Disclosed are multichromophores, and methods, articles and compositions employing them. Disclosed are methods, articles and compositions for the detection and analysis of biomolecules in a sample. Provided assays include those determining the presence of a target biomolecule in a sample or its relative amount, or the assays may be quantitative or semi-quantitative. The methods can be performed on a substrate or in an array format on a substrate. Disclosed are detection assays employing sensor biomolecules that do not comprise a fluorophore that can exchange energy with the cationic multichromophore. Disclosed are biological assays in which energy is transferred between one or more of the multichromophore, a label on the target biomolecule, a label on the sensor biomolecule, and/or a fluorescent dye specific for a polynucleotide, in all permutations.
A water-soluble conjugated polymer comprising a plurality of solubilizing functionalities, said polymer soluble in a polar medium,
A kit for assaying a sample for a target biomolecule comprising:
A polymer prepared by Suzuki copolymerization of 2,7-bis[9,9′-bis(6″-bromohexyl)-fluorenyl]-4,4,5,5-tetramethyl-[1.3.2]dioxaborolane and 4,7-dibromo-2,1,3-benzothiadiazole.
Dependencies are inferred from the claim text.