Dividable galenical form allowing modified release of the active ingredient
AssigneeLes Laboratoires Servier
InventorsGilles FONKNECHTEN, Patrick Genty, Jean-Manuel Pean, Patrick Wuthrich
Life of this patent
Estimating the term…
Abstract
Dividable galenical form for the modified release of active ingredient, wherein the non-subdivided galenical form and a portion of said form obtained by subdivision have identical dissolution profiles.
Claims14
A dividable prolonged-release tablet comprising gliclazide, a cellulose derivative, wherein the cellulose derivative comprises from 50 to 60% of the total weight of the tablet, and a binder, wherein the tablet which has not been subdivided and a half tablet which is obtained by subdividing the tablet have similar dissolution profiles, which dissolution profiles are both largely linear over the time of dissolution.
The tablet of claim 6, wherein the hydrophilizing agent is colloidal silica.
Dependencies are inferred from the claim text.