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US 2013/0295013 A1Published application
Solid composition for the oral administration of dyes and diagnostic use thereof
AssigneeCosmo Technologies Limited
InventorsLuigi MORO, Mauro Severino AJANI, Roberto VILLA, Giuseppe CELASCO, Alessandro REPICI
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Abstract
The present application discloses solid compositions for the oral administration of dyes, and diagnostic use thereof. Preferably, such diagnostic use is aimed at the diagnostic evaluation of the gastrointestinal tract.
Claims19
A solid composition for oral administration containing at least one dye in association with at least one physiologically acceptable excipient, said composition comprising:
- (a) at least one dye selected from among methylene blue, congo red, carmine indigo, toluidine blue or mixtures thereof;
- (b) a first matrix in which said at least one dye is incorporated, wherein said first matrix comprises at least one lipophilic compound having a melting point below 90° C. and at least one amphiphilic compound;
- (c) a second matrix comprising at least one hydrophilic compound, wherein the first matrix is dispersed in the second matrix;
- (d) optionally other physiologically acceptable excipients;
- and
- (e) optionally a gastro-resistant coating.
3 more elements
Dependencies are inferred from the claim text.