Methods of Treating Acute Kidney Injury Using Mesenchymal Stem Cells
AssigneeAllocure, Inc.
InventorsDena Minning, Robert M. Brenner
Life of this patent
Estimating the term…
Abstract
The invention relates to methods of treating acute kidney injury (AKI) in a patient by administering a therapeutic amount of mesenchymal stem cells (MSC) to a patient in need thereof. Administration of MSCs ameliorates AKI in the patient when administered up to at least 48 hours following kidney injury or decline in kidney function.
Claims35
A method of treating acute kidney injury (AKI) in a subject comprising administering a therapeutically effective amount of human mesenchymal stem cells (hMSC) to a subject in need thereof up to at least 48 hours following a decline in kidney function in the subject, wherein the decline in kidney function is measured by an increase in serum creatinine level of at least 0.3 mg/dL, and wherein the hMSCs ameliorate AKI in the subject.
Dependencies are inferred from the claim text.