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US 2013/0274342 A1Published application
Compositions and methods for treating cough
AssigneeCerecor, Inc.
InventorsMark GINSKI, Blake PATERSON, Reza MAZHARI, Djelila MEZAACHE
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Abstract
Compositions, methods of making compositions and methods of treating cough are described herein. In some embodiments, the compositions are lozenges comprising memantine and an alkalinizing agent.
Claims40
A compressed antitussive lozenge comprising:
- memantine, or a pharmaceutically acceptable salt thereof;
- menthol;
- and an alkalinizing agent, wherein after a single buccal or sublingual administration, said compressed antitussive lozenge provides a memantine AUC0-1 hr ranging from about 1.0 ng-hr/mL to about 10 ng-hr/mL.
Dependencies are inferred from the claim text.