Fulvestrant compositions and methods of use
AssigneeShimoda Biotech (Pty) Ltd
InventorHenk Swart
Life of this patent
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Abstract
Provided are inclusion complexes comprising fulvestrant and a cyclodextrin. The complexes may be useful for treating various conditions, such as cancer and systemic lupus crythematosus. Also provided are methods of producing the inclusion complexes, methods of using the inclusion complexes in therapy, and kits and unit dosages comprising the complexes.
Claims26
An inclusion complex comprising a) a cyclodextrin;
- and b) a compound of the formula (I):
- or a salt thereof or hydrate of the foregoing;
- and c) a carrier.
A formulation comprising a) a cyclodextrin;
- b) a compound of the formula (I):
- or a salt thereof or hydrate of the foregoing;
- and c) a carrier.
13-21. (canceled)
25-30. (canceled)
The method of claim 30, wherein the method further comprises administering one other anti-cancer agent.
32-35. (canceled)
37-44. (canceled)
46-48. (canceled)
A method for improving solubility of a compound of the formula (I):
- or a salt, hydrate, or solvate thereof in water comprising complexing the compound of the formula (I) with a cyclodextrin.
51-76. (canceled)
Dependencies are inferred from the claim text.