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US 2013/0274222 A1Published application
Threads of cross-linked hyaluronic acid and methods of preparation and use thereof
AssigneeTauTona Group LP
InventorsKenneth N. Horne, Vivek Shenoy, Naveen Jayakumar, Geoffrey C. Gurtner
Life of this patent
Estimating the term…
Abstract
This disclosure relates generally to cross-linked hyaluronic acid compositions, threads made from such compositions, methods of making such threads and uses thereof, for example, in aesthetic applications (e.g., facial contouring, soft tissue augmentation products), surgery (e.g., sutures), drug delivery, negative pressure wound therapy, moist wound dressing, and the like.
Claims24
-9. (canceled)
A method for making a cross-linked hyaluronic acid thread, comprising:
- a) combining hyaluronic acid and butanediol diglycidyl ether in an aqueous composition until the hyaluronic acid is substantially cross-linked to provide a substantially cross-linked composition, wherein the ratio of hyaluronic acid to cross-linking agent in the combining step is from about 1:2 to about 10:1;
- b) extruding the substantially cross-linked composition to provide a wet thread;
- and
- c) drying the wet thread to provide a cross-linked hyaluronic acid thread.
1 more element
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Dependencies are inferred from the claim text.