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US 2013/0274202 A1Published application
Peptides for Treating Cancer
AssigneeGene Signal International SA
InventorsSalman Al-Mahmood, Sylvie Colin
Life of this patent
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Abstract
The present invention relates to peptide from 4 to 50 amino acids comprising a phosphorylated pYX1X2X1 motif (SEQ ID NO: 1), wherein each X1 independently is M or Nle and X2 is any amino acid, pharmaceutical compositions comprising said peptide and use thereof for treating cancer.
Claims21
-16. (canceled)
A peptide comprising a phosphorylated pYX1X2X1 motif (SEQ ID NO:
- 1) wherein:
- each X1 independently is M or Nle and X2 is any amino acid;
- the peptide comprises from 4 to 50 amino acids;
- and
- the peptide is not a peptide of SEQ ID NO:
- 2, SEQ ID NO:
- 3, SEQ ID NO:
- 4, SEQ ID NO:
- 5, SEQ ID NO:
- 6, SEQ ID NO:
- 7, SEQ ID NO:
- 8, SEQ ID NO:
- 9, SEQ ID NO:
- 10, SEQ ID NO:
- 11, SEQ ID NO:
- 12, SEQ ID NO:
- 13, SEQ ID NO:
- 29, SEQ ID NO:
- 30, SEQ ID NO:
- 31, SEQ ID NO:
- 32, SEQ ID NO:
- 41, SEQ ID NO:
- 43, SEQ ID NO:
- 44, SEQ ID NO:
- 45, SEQ ID NO:
- 46, SEQ ID NO:
- 47, SEQ ID NO:
- 48, SEQ ID NO:
- 49, SEQ ID NO:
- 50, SEQ ID NO:
- 51, SEQ ID NO:
- 52, SEQ ID NO:
- 53, SEQ ID NO:
- 54, SEQ ID NO:
- 55, SEQ ID NO:
- 56, SEQ ID NO:
- 57, SEQ ID NO:
- 58, SEQ ID NO:
- 59, SEQ ID NO:
- 60, SEQ ID NO:
- 61, SEQ ID NO:
- 62, SEQ ID NO:
- 63, or SEQ ID NO:
- 64.
41 more elements
A composition comprising a peptide from 4 to 50 amino acids comprising a phosphorylated pYX1X2X1 motif (SEQ ID NO:
- 1), wherein each X1 independently is M or Nle and X2 is any amino acid.
A method of treating a subject comprising:
- obtaining a therapeutically sufficient amount of a peptide from 4 to 50 amino acids comprising a phosphorylated pYX1X2X1 motif (SEQ ID NO:
- 1), wherein each X1 independently is M or Nle and X2 is any amino acid;
- and
- administering the amount of peptide to the subject;
- wherein a cancer and/or an angiogenesis-related disease is treated in the subject.
2 more elements
Dependencies are inferred from the claim text.