US 2013/0274188 A1 · MACROMOLECULE FOR DELIVERING PROTEIN, POLYPEPTIDE OR PEPTIDE DRUGS AND A PRODUCTION METHOD FOR THE SAME, AND A SLOW RELEASE COMPOSITION FOR PROTEIN, POLYPEPTIDE OR PEPTIDE DRUGS AND A PRODUCTION METHOD FOR THE SAME

Abstract

The present invention relates to a macromolecule for delivering protein, polypeptide or peptide drugs and to a production method for the same, as well as to a slow release composition for protein, polypeptide or peptide drugs comprising the same, and more specifically relates to a polylactic acid derivative compound of Chemical formula 1 of which the numerical average molecular weight is no more than 7000 daltons and to a production method for the same, as well as to a slow release composition for protein, polypeptide or peptide drugs using the same and to a production method for the same.

Claims23

Dependent claims

A polylactic acid derivative compound of the following chemical formula 1 having a number average molecular weight of no more than 7,000 daltons:

wherein in the above chemical formula 1,
X and X′ are independently hydrogen, alkyl or aryl,
Y and Z are independently absent or an alkali metal,
m and n are independently an integer of 0 to 95, provided that 5<m+n<100,
a and b are independently an integer of 1 to 6,
R is unsubstituted or substituted —(CH2)k- where k is an integer of 0 to 10, a divalent alkenyl having 2 to 10 carbon atoms, a divalent aryl having 6 to 20 carbon atoms, or a combination thereof.

3 more elements

Dependencies are inferred from the claim text.

Facts

Application

13/519,729Filed 28 Dec 2010

Priority

KR 10-2009-013286129 Dec 2009

Published

17 Oct 2013

Term ends

Not estimatedThe source records don’t support an estimate.

Classification11 codes

A61K 47/34
Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates: macromolecular compounds obtained otherwise than by reactions only…
C07C 67/465
Preparation of carboxylic acid esters: by oligomerisation
C07C 69/68
Of saturated hydroxy-carboxylic acids: lactic acid esters
C08G 63/06
Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds: derived from hydroxycarboxylic acids

Macromolecule for delivering protein, polypeptide or peptide drugs and a production method for the same, and a slow release composition for protein, polypeptide or peptide drugs and a production method for the same

Life of this patent

Macromolecule for delivering protein, polypeptide or peptide drugs and a production method for the same, and a slow release composition for protein, polypeptide or peptide drugs and a production method for the same

Life of this patent

Abstract

Claims23