Diagnostic marker for melanoma, pharmaceutical composition comprising inhibitor of the function of the histatin-1 protein and immunosuppressor
AssigneeKeio University
InventorsTomonori Yaguchi, Yutaka Kawakami
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Abstract
The present invention is directed to provide diagnostic markers for melanoma, novel pharmaceutical compositions, and novel immunosuppressors. The histatin-1 mRNA and the histatin-1 protein can be used as the diagnostic markers for melanoma. In addition an inhibitor of the function that inhibits the function of the histatin-1 protein may be used as a pharmaceutical composition. Furthermore, a dendritic cell differentiated from a monocyte by the action of the histatin-1 protein or the histatin-1 protein may be used as an immunosuppressor.
Claims4
An immunosuppressor comprising a histatin-1 protein.
A method of producing an immunosuppressive dendritic cell comprising the step of:
- differentiating a monocyte isolated from human or a non-human vertebrate in the presence of a histatin-1 protein.
Dependencies are inferred from the claim text.