Back to results
US 2013/0273085 A1Published application
Novel P2X7 Epitopes
AssigneeBiosceptre International Limited
InventorsJulian Alexander Barden, Angus Gidley-Baird
Life of this patent
Estimating the term…
Abstract
The invention relates to purinergic (P2X) receptors, more specifically to P2X7 receptors, the generation of antibodies and the use of antibodies and immunogens that are capable of selectively binding to a non ATP-binding P2X7 receptor but not to an ATP-binding P2X7 receptor, for the detection and treatment of disease conditions, especially cancer.
Claims9
1-9. (canceled)
A peptide consisting of the sequence shown in SEQ ID NO:
- 3 or consisting of a sequence within the sequence shown in SEQ ID NO:
- 3, said peptide being useful as an immunogen to generate an antibody that is capable of selectively binding to a non ATP-binding P2X7 receptor but not to an ATP-binding P2X7 receptor.
A peptide consisting of the sequence shown in SEQ ID NO:
- 4, SEQ ID NO:
- 5, SEQ ID NO:
- 6, SEQ ID NO:
- 7, SEQ ID NO:
- 8 or SEQ ID NO:
- 9.
3 more elements
Dependencies are inferred from the claim text.