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US 2013/0259933 A1Published application
Capsule which disintegrates specifically in the large intestine
AssigneeMorishita Jintan Co., Ltd.
InventorsRyosei KAMAGUCHI, Masafumi MIZUTANI
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Abstract
The present invention is to obtain capsules which do not disintegrate in stomach and intestine after orally administrating them and which disintegrate specifically in large intestine. The present invention thus provides a capsule which disintegrates specifically in large intestine, comprising a content comprising a main agent, and a shell, covering the content, comprising a natural water-soluble polymer as a shell base material and chitosan powder dispersing in the natural water-soluble polymer.
Claims10
A capsule comprising:
- a composition comprising a main agent, and
- a shell that coats the composition,
- wherein the shell comprises a natural water-soluble polymer as a shell base material and chitosan powder that is dispersed within the natural water-soluble polymer,
- wherein the natural water-soluble polymer is a mixture of a first natural water-soluble polymer and a second natural water-soluble polymer, wherein the first natural water-soluble polymer is at least one selected from the group consisting of gelatin, carrageenan, starch, agar, pullulan, modified starch, alginic acid and mannan, and the second natural water-soluble polymer is at least one selected from the group consisting of pectin, gellan gum and cardlan, and
- wherein the shell is an outermost layer of the capsule and allows delivery of the capsule in a large intestine to be disintegrated.
2 more elements
(canceled)
Dependencies are inferred from the claim text.