Progenitor cells from wharton's jelly of human umbilical cord
AssigneeTissue Regeneration Therapeutics Inc.
InventorsJohn E. Davies, Dolores Baksh, Rahul Sarugaser, Morris Hosseini, Antony D.S. Lickorish
Life of this patent
Estimating the term…
Abstract
Human progenitor cells are extracted from perivascular tissue of human umbilical cord. The progenitor cell population proliferates rapidly, and harbours osteogenic progenitor cells and MHC−/− progenitor cells, and is useful to grow and repair human tissues including bone.
Claims20
An isolated Wharton's jelly extract, wherein the extract comprises human progenitor cells and is obtained by enzymatic digestion of the perivascular tissue proximal to the vasculature of human umbilical cord.
An isolated cell population useful as a source of human progenitor cells, wherein the cell population is extractable from perivascular tissue of human umbilical cord, and has the characteristics of (1) rapid proliferation, (2) the presence of osteoprogenitor cells, and (3) the presence of immuno-incompetent cells.
An isolated population of human progenitor cells, wherein at least 50% of the cells in said population have an MHC double negative phenotype.
Dependencies are inferred from the claim text.