3,5-Disubstituted and 3,5,7-Trisubstituted-3H-Oxazolo and 3H-Thiazolo[4,5-d]pyrimidin-2-one Compounds and Prodrugs Thereof
AssigneeAnadys Pharmaceuticals, Inc.
InventorsStephen E. Webber, Gregory J. Haley, Joseph R. Lennox, Alan Xin Xiang, Erik J. Rueden
Life of this patent
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Abstract
The invention is directed to 3,5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs thereof that have immunomodulatory activity. The invention is also directed to the therapeutic or prophylactic use of such compounds and pharmaceutical compositions containing them, and to methods of treating diseases and disorders described herein, by administering effective amounts of such compounds and prodrugs.
Claims16
1-40. (canceled)
A method of treating a tumor or cancer caused by a virus comprising administering to a patient a therapeutically effective amount of a compound selected from the group consisting of:
- or a pharmaceutically acceptable salt or tautomer thereof,
- wherein the virus is hepatitis C.
A method of treating a tumor or cancer caused by a virus comprising administering to a patient a therapeutically effective amount of a compound that is
- or a pharmaceutically acceptable salt thereof,
- wherein the virus is hepatitis C.
A method of treating a tumor or cancer caused by a virus comprising administering to a patient a therapeutically effective amount of a compound that is
- or a pharmaceutically acceptable salt or tautomer thereof,
- wherein the virus is hepatitis C.
Dependencies are inferred from the claim text.