Apparatus and method for molecular separation, purification, and sensing
AssigneeLux Bio Group, Inc.
InventorGordon HOLT
Life of this patent
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Abstract
Described are devices and methods for forming one or more nanomembranes including electroactive nanomembranes within a nanowell or nanotube, or combinations thereof, in a support material. Nanopores/nanochannels can be formed by the electroactive nanomembrane within corresponding nanowells. The electroactive nanomembrane is capable of controllably altering a dimension, a composition, and/or a variety of properties in response to electrical stimuli. Various embodiments also include devices/systems and methods for using the nanomembrane-containing devices for molecular separation, purification, sensing, etc.
Claims21
A method of forming a device comprising:
- providing an array formed by one or more of a nanowell, a nanotube, and combinations thereof, in a support material, the nanotube comprising one or more sidewall electrodes, the nanowell comprising one or more sidewall electrodes and/or one or more bottom electrodes;
- and
- depositing an electroactive nanomembrane over at least a portion of one electrode in the array, wherein the electroactive nanomembrane is configured to change at least one dimension of the electroactive nanomembrane resulting from an electroactive response.
A method of forming a device comprising:
- providing an array formed by one or more nanowells or nanotubes or combinations thereof in a support material, each nanotube comprising one or more sidewall electrodes, each nanowell comprising one or more sidewall electrodes and/or one or more bottom electrode;
- depositing a first nanomembrane over at least a portion of one electrode of the array;
- and
- tunably depositing a second electroactive nanomembrane over the first nanomembrane to form a nanochannel or nanopore, or combinations thereof, within a corresponding nanowell or a corresponding nanotube in the array, wherein the second electroactive nanomembrane is configured to alter one or more of a molecular composition, a dimension, or a property thereof in response to electrical stimuli.
A method of forming a device comprising:
- providing one or more nanowells or nanotubes or combinations thereof in a support material, each nanotube comprising one or more sidewall electrodes, each nanowell comprising one or more sidewall electrodes and/or one or more bottom electrodes;
- selecting a first precursor material;
- depositing a first nanomembrane from the first precursor material over at least a portion of one electrode of the one or more nanowells or nanotubes or combinations thereof;
- replacing the first precursor material with a second precursor material;
- and
- electrochemically depositing a second electroactive nanomembrane over the first nanomembrane from the second precursor material to form a nanopore or nanochannel within a corresponding nanowell or nanotube, wherein at least a portion of the first or second electroactive nanomembrane comprises a chemically reactive material, a charge-binding material, a hydrophobic material, a hydrophilic material, a charged material, a metal-binding material, a metallic material, an electro-conducting material, or combinations thereof.
Dependencies are inferred from the claim text.