# US 2013/0239690 A1 · Mre excitation apparatus, excitation system, and excitation method

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- Number: US 2013/0239690 A1
- Document ID: US20130239690A1
- Status: Published application
- Kind: A1
- Application number: 13/818,964
- Filed: 2011-08-25
- Published: 2013-09-19
- Earliest claimed: 2010-08-25
- Assignees: National University Corporation Chiba University
- Inventors: Shigeru Tadano; Itsuro Kajiwara; Kazuhiro Fujisaki; Seishin Takao; Gen Nakamura; Yu Jiang; Mikio Suga
- Web page: https://patentgrep.com/patent/US20130239690A1

## CPC

- G01N 29/04: Analysing solids (using acoustic emission techniques G01N29/14)
- A61B 5/0051: {by applying vibrations}
- A61B 5/055: involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
- A61B 5/704: {Tables}
- G01R 33/56358: {Elastography}
- G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G01R: MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES (indicating correct tuning of resonant circuits H03J3/12)

## Abstract

An MRE excitation apparatus (100) comprises an excitation device (110) that generates vibration, and a transmitter (120) that is made using a non-magnetic material and that, with one end-section being fastened to the excitation device (110) and the other end-section being connected with a living body (300), and that extends in direction that vibration is transmitted from the excitation device (110) and transmits longitudinal vibration from the excitation device (110) to the living body (300). The frequency of the vibration is 125 Hz or greater, the amplitude of the vibration is 0.2 mm or greater, and the primary natural frequency of the longitudinal vibration of the transmitter (120) is further on the higher side than the frequency band of the vibration from the excitation device (110).

## Claims

### Claim 1

An MRE excitation apparatus that excites a test object during MRE measurement, comprising:
an excitation device that generates vibration; and
a transmitter that is made using a non-magnetic material and that, with one end-section being fastened to the excitation device and the other end-section connecting to the test object, extends along the direction of vibration from the excitation device and transmits longitudinal vibration from the excitation device to the test object; wherein
the frequency of the vibration is 125 Hz or greater;
the amplitude of the vibration is 0.2 mm or greater; and
the primary natural frequency of the longitudinal vibration of the transmitter is further on the high side than the frequency band of the vibration from the excitation device; and
the MRE excitation apparatus further comprises a support that is located between the one end-section and the other end-section of the transmitter, and that supports the transmitter.

### Claim 2

An MRE excitation apparatus that excites a test object during MRE measurement, comprising:
an excitation device that generates vibration;
a transmitter that is made using a non-magnetic material and that extends along the direction that vibration is transmitted from the excitation device;
at least one direction changer; and
a transmitter on the test object side that is made using a non-magnetic material and that extends in an angle different than the direction that the transmitter extends; wherein
the one end-section of the transmitter is fastened to the excitation device, the other end-section of the transmitter is connected to the direction changer, and the transmitter transmits longitudinal vibration from the excitation device to the direction changer;
the direction changer changes the direction of the longitudinal vibration that is transmitted by the transmitter, and transmits the longitudinal vibration to the transmitter on the test object side;
the transmitter on the test object side is connected with the test object, and transmits the longitudinal vibration to the test object;
the frequency of the vibration is 125 Hz or greater;
the amplitude of the vibration is 0.2 mm or greater; and
the primary natural frequency of the longitudinal vibration of the transmitter and the transmitter on the test object side is further on the high side than the frequency band of the vibration from the excitation device; and
the MRE excitation apparatus further comprises a support that is located between the one end-section and the other end-section of the transmitter, and that supports the transmitter.

### Claim 3 (depends on 1)

The MRE excitation apparatus according to claim 1, wherein the transmitter is made using a non-metallic material.

### Claim 4 (depends on 1)

The MRE excitation apparatus according to claim 1, wherein the transmitter is made using a GFRP material.

### Claim 5

(canceled)

### Claim 6 (depends on 1)

The MRE excitation apparatus according to claim 1, wherein the support is made using a soft material, and has a holder that holds the transmitter.

### Claim 7

An MRE excitation system that excites a test object during MRE measurement, comprising:
an excitation device that generates vibration; and
a transmitter that transmits longitudinal vibration from the excitation device to the test object; wherein
the frequency of the vibration is 125 Hz or greater;
the amplitude of the vibration is 0.2 mm or greater;
the primary natural frequency of the longitudinal vibration of the transmitter is further on the high side than the frequency band of the vibration from the excitation device; and
during the MRE measurement, the frequency and amplitude of the longitudinal vibration that is generated by the excitation device is controlled so that variation in measurement values of the modulus of elasticity in the measurement area in the test object is minimized; and
the MRE excitation apparatus further comprises a support that is located between one end-section and the other end-section of the transmitter, and that supports the transmitter.

### Claim 8 (depends on 7)

The MRE excitation system according to claim 7 comprising a controller that automatically controls the frequency and amplitude of the vibration.

### Claim 9

An MRE excitation method comprising:
controlling the frequency and amplitude of longitudinal vibration so that variation in measurement values of modulus of elasticity in a measurement area in a test object is minimized;
generating vibration; and
exciting the test object with the longitudinal vibration; wherein
the frequency of the vibration is 125 Hz or greater; and
the amplitude of the vibration is 0.2 mm or greater.

### Claim 10 (depends on 9)

The MRE excitation method according to claim 9, wherein the controlling the frequency and amplitude of the vibration is automatically controlled.

### Claim 11 (depends on 2)

The MRE excitation apparatus according to claim 2, wherein the transmitter is made using a non-metallic material.

### Claim 12 (depends on 2)

The MRE excitation apparatus according to claim 2, wherein the transmitter is made using a GFRP material.

### Claim 13 (depends on 2)

The MRE excitation apparatus according to claim 2, wherein the support is made using a soft material, and has a holder that holds the transmitter.
