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US 2013/0231484 A1Published application
Compounds having photochemically removable protecting groups based on an electrocyclic reaction between a chromophore attached via an anilide group to a benzothiophene ring
AssigneeMarquette University
InventorsMark G. Steinmetz, Majher I. Sarker, Tasnuva Shahrin
Life of this patent
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Abstract
Disclosed herein are compounds having photoremovable protecting groups which are removed after the compounds absorbs light of a given wavelength and undergo an electrocyclic reaction between a chromophore in the compound attached via an anilide to a benzothiophene ring.
Claims20
A compound having a formula:
- W and X are hydrogen or —COOY, wherein at least one of W and X is —COOY, and Y is hydrogen or C1-C6 alkyl;
- LG− is Cl−, PhCH2CO2−, PhS−, PhCH2S−, PhO−, HO−, or HS−;
- R is C1-C6 alkyl;
- and A is a chromophore that is photochemically stimulated to react with the carbon atom bearing LG and photolyze LG from the compound.
1 more element
A method for forming a reaction product having a formula
- wherein R is C1-C6 alkyl,
- Z is S or O,
- R1, R2, R4, and R4 are each independently halogen or hydrogen,
- W and X are hydrogen or —COOY, wherein Y is hydrogen or C1-C6, alkyl, and LG− is Cl−, PhCH2CO2−, PhS−, PhCH2S−, PhO−, HO−, or HS−,
- the method comprising reacting:
- (a) a compound having a formula:
- (b) a compound having a formula:
4 more elements
Dependencies are inferred from the claim text.