Engineered surfaces for reducing bacterial adhesion
Assignee3M Innovative Properties Company
InventorsG. Marco Bommarito, Matthew T. Scholz, Michael J. Svarovsky, Jeremy M. Yarwood, Scott M. Schnobrich, Robert J. DeVoe, Jun-Ying Zhang, Terry L. Smith
Life of this patent
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Abstract
Disclosed are surfaces for resisting and reducing biofilm formation, particularly on medical articles (100). The surfaces include a plurality of microstructures (120) including a plurality of nanofeatures (140) arranged according to at least one unit cell. Also disclosed are methods for creating anti-adherent surfaces.
Claims23
An apparatus having bacterial anti-adhesion properties comprising:
- a body having an engineered surface, at least a portion of said surface comprising a plurality of engineered structures, wherein the nanofeatures comprise inorganic nanoparticles;
- a plurality of randomly distributed, directed nanofeatures disposed on at least a portion of the engineered structures;
- wherein the plurality of engineered structures comprise at least one periodic structure, wherein the periodic structure comprises at least one dimension of at least 0.5 microns and no greater than 50 microns, and
- wherein the pitch between adjacent structures of the plurality of engineered structures is at least 0.1 and no greater than 150 microns.
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A method of creating an anti-adhesion surface, the method comprising:
- providing a base device comprising an outer contact surface;
- creating a plurality of engineered structures on the outer contact surface to form an engineered surface, wherein the plurality of engineered structures comprise a pattern, said pattern comprising a periodic structure, and wherein the periodic structure comprises at least one dimension of at least 0.5 microns and no greater than 50 microns, and wherein the plurality of structures comprises a pitch of at least 0.5 microns and no greater than 150 microns;
- creating a plurality of directed nanofeatures on at least one structure of the plurality of engineered structures by applying a layer of nanoparticles to the engineered surface;
- and etching the surface using the layer of nanoparticles as an etch mask.
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Dependencies are inferred from the claim text.