Compositions suitable for the topical treatment of fungal infections of the skin and nails

A method of treating a fungal infection of the skin or nails comprising administering to a subject a therapeutically effective amount of a topical antifungal composition, said composition being non-toxic and compatible with the skin, and comprising a combination of two or more low molecular weight organic acids or their salts, dissolved in a carrier, wherein,

• the low molecular weight organic acids are selected from the group consisting of:
• saturated and unsaturated, cyclic and acyclic, branched and unbranched aliphatic carboxylic acids containing less than 15 carbon atoms,
• aromatic carboxylic acids containing fewer than 15 carbon atoms, and
• the corresponding sulfonic and phosphonic acid derivatives of said aliphatic and aromatic carboxylic acids;
• wherein the organic acids are unsubstituted or substituted with one or more of alkyl, alkenyl, alkynyl, halogen, hydroxy, carbonyl, carboxylic acid, aldehyde, ester, amide, carbonate, carbamate, ether, amino, cyano, isocyano, oxy, oxo, thia, aza, azide, imine, nitro, nitrate, nitroso, nitrosooxy, cyanate, isocyanate, thiocyanate, isothiocyanate, sulfinyl, sulfhydryl, sulfonyl, and phosphino functional groups, wherein each of the alkyl, alkenyl, alkynyl and amino groups is unsubstituted or substituted with one or more of the preceding functional groups;
• the carrier consists essentially of one or more non-volatile, hygroscopic solvents;
• and
• wherein the combination of low molecular weight organic acids or salts comprises 0.1% to 50% by weight of the composition, and no single acid or salt comprises more than 75% by weight of the total acid or salt content.