Loading patent…
AssigneeCity of Hope
InventorsBehnam BADIE, Leying ZHANG, Darya ALIZADEH, Dongchang ZHAO, Jacob BERLIN
Estimating the term…
One aspect of the invention relates to a nanoparticle conjugated CpG (NANO-CpG) composition and pharmaceutical composition thereof, and the preparation methods thereof. Another aspect of the invention relates to a method for using the NANO-CpG to improve CpG delivery into brain tumor associated inflammatory cells in a subject. Another aspect of the invention relates to a method for treating or preventing a method for treating and/or preventing a brain tumor in a subject comprising administering a therapeutically effective amount of the NANO-CpG or a pharmaceutical composition thereof to the subject. In one embodiment, a subject treated with the NANO-CpG composition disclosed herein or a pharmaceutical composition thereof developed immunity to brain tumor.
A method comprising administering a therapeutically effective amount of nanoparticle (NANO) conjugated CpG (NANO-CpG) or a pharmaceutical composition thereof to a subject, wherein the NANO-CpG administration improves the CpG delivery into brain tumor associated inflammatory cells in the subject compared to an administration of free CpG of the same amount.
A method for treating and/or preventing a brain tumor in a subject comprising administering a therapeutically effective amount of NANO-CpG or a pharmaceutical composition thereof to the subject.
A composition prepared by a method comprising:
A composition comprising:
Dependencies are inferred from the claim text.