Alpha-2 adrenergic agonist having long duration of intraocular pressure-lowering effect
AssigneeAllergan, Inc.
InventorsJOHN E. DONELLO, DANIEL W. GIL, MOHAMMED I. DIBAS
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Abstract
The present invention provides a method of lowering intraocular pressure which comprises administering a therapeutically effective amount of a pharmaceutical composition comprising 4-bromo-5-(2-imidazolin-2-ylamino)benzimidazole, or a salt thereof to the affected eye of a patient, as a single dose, wherein the affected eye maintains an intraocular pressure less than the baseline thereafter.
Claims12
A method of lowering intraocular pressure which comprises administering by direct injection into the back of the eye a therapeutically effective amount of a pharmaceutical composition comprising 4-bromo-5-(2-imidazolin2-ylamino)benzimidazole or a salt thereof, to the affected eye of a patient, in need thereof, as a single dose.
A method of lowering intraocular pressure of a patient in need thereof which comprises administering by injection into the back of the eye a therapeutically effective amount of a pharmaceutical composition comprising 4-bromo-5-(2-imidazolin-2-ylamino)benzimidazole or a salt thereof, to the affected eye of said patient, once daily, wherein the affected eye maintains an intraocular pressure less than the baseline intraocular pressure, throughout the day.
A method of lowering intraocular pressure which comprises administering via intracameral route a therapeutically effective amount of a pharmaceutical composition comprising 4-bromo-5-(2-imidazolin2-ylamino)benzimidazole or a salt thereof, to the affected eye of a patient, in need thereof, as a single dose.
A method of lowering intraocular pressure which comprises administering via intravitreal route a therapeutically effective amount of a pharmaceutical composition comprising 4-bromo-5-(2-imidazolin2-ylamino)benzimidazole or a salt thereof, to the affected eye of a patient, in need thereof, as a single dose.
Dependencies are inferred from the claim text.