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US 2013/0210872 A1Published application
Combination therapy using riluzole to enhance tumor sensitivity to ionizing radiation
AssigneeUniversity of Medicine and Dentistry of New Jersey
InventorsAtif Jalees Khan, Suzie Chen, James S. Goydos, Bruce G. Haffty
Life of this patent
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Abstract
Disclosed is a method of treating a tumor in a patient, comprising (a) administering riluzole in an amount effective to sensitize the tumor cells to ionizing radiation, and (b) irradiating the tumor cells with ionizing radiation in a dose effective to reduce tumor cell growth. The method can further comprise administering an effective amount of one or more additional therapeutic agents.
Claims20
A method of treating a tumor in a patient, said tumor comprising cells expressing a metabotropic glutamate receptor, said method comprising:
- (a) administering riluzole in an amount effective to sensitize the tumor cells to ionizing radiation, and
- (b) irradiating the tumor cells with ionizing radiation in a dose effective to reduce tumor cell growth.
Dependencies are inferred from the claim text.