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US 2013/0210852 A1Published application
Methods for treating infection
OwnerHerbert L. DuPont, Zhi-Dong Jiang +3inventors
InventorsHerbert L. DuPont, Zhi-Dong Jiang, Eric Brown, Charles Darkoh, Pam Golden
Life of this patent
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Abstract
The present invention provides new methods and kits for treating and preventing bacterial infection.
Claims31
A method of treating a C. difficle infection (CDI) in a subject, comprising:
- administering rifaximin to a subject,
- thereby treating CDI.
A method of altering the virulence of bacteria causing Traveler's Diarrhea (TD) in a subject, comprising:
- administering rifaximin to a subject having TD;
- thereby altering the virulence of the bacteria causing TD.
A method for decreasing the ability of bacteria to attach to epithelial calls comprising:
- contacting the epithelial cells with rifaximin prior to exposure to the bacteria,
- thereby decreasing the ability of the bacteria to attach to the epithelial cells.
A method of preventing a disease or disorder characterized by bacterial adhesion to epithelial cells of a subject, comprising:
- administering rifaximin to a subject prior to exposure to the bacteria,
- thereby preventing a disease or disorder characterized by bacterial adhesion to epithelial calls.
Dependencies are inferred from the claim text.