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US 2013/0210847 A1Published application
Process for the preparation of nilotinib
AssigneeNatco Pharma Limited
InventorsAmala Kompella, Adibhatla Kali Satya Bhujanga Rao, Sreenivas Rachakonda, Venugopala Krishna Gampa, Venkaiah Chowdary Nannapaneni
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Abstract
The present invention relates a process for the preparation of a compound of formula (I): or a pharmaceutically acceptable salt thereof, which process comprises converting a compound of formula (IV): or a pharmaceutically acceptable salt thereof, into the compound of formula (I) or a pharmaceutically acceptable salt thereof.
Claims13
A process for the preparation of a compound of formula (I):
- or a pharmaceutically acceptable salt thereof,
- which process comprises converting a compound of formula (IV):
- or a pharmaceutically acceptable salt thereof, into the compound of formula (I) or a pharmaceutically acceptable salt thereof.
A compound of formula (IV):
- or a pharmaceutically acceptable salt thereof.
A compound of formula (V):
- or a pharmaceutically acceptable salt thereof.
A compound of formula (III):
- or a pharmaceutically acceptable salt thereof.
A crystalline form of a compound of formula (I):
- or a pharmaceutically acceptable salt thereof, which has an X-ray powder diffraction pattern with one or more peaks at 4.3, 8.7, 9.5, 11.3, 13.2, 14.4, 17.3, 18.6, 19.3, 20.8, 22.2 and 25.3 degrees 2θ (±0.1 degrees 2θ).
Dependencies are inferred from the claim text.