Therapeutic compositions
AssigneeActelion Pharmaceuticals Ltd.
InventorMartine CLOZEL
Life of this patent
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Abstract
The invention relates to a product containing the compound of formula (I) below (I) or a pharmaceutically acceptable salt of this compound, in combination with at least one compound having PDE5-inhibitory properties, or a pharmaceutically acceptable salt thereof, for therapeutic use, simultaneously, separately or over a period of time, in the treatment of a disease wherein vasoconstriction is involved.
Claims14
A method for the treatment of hypertension, pulmonary hypertension or pulmonary arterial by comprising administering simultaneously, separately or over a period of time, to a patient in need thereof, an effective amount of a compound of formula (I):
- in free or pharmaceutically acceptable salt form, and at least one compound having PDE5-inhibitory properties, in free or pharmaceutically acceptable salt form.
A method for the treatment of pulmonary arterial hypertension, comprising administering to a patient in need thereof, simultaneously, an effective amount of a compound of formula (I):
- in free or pharmaceutically acceptable salt form, and at least one sildenafil or tadalafil, in free or pharmaceutically acceptable salt form.
A method for the treatment of pulmonary arterial hypertension, comprising administering over a period of time, to a patient in need thereof, an effective amount of a compound of formula (I):
- in free or pharmaceutically acceptable salt form, and at least one sildenafil or tadalafil, in free or pharmaceutically acceptable salt form.
A method for the treatment of pulmonary arterial hypertension, comprising administering to a patient in need thereof, separately, an effective amount of a compound of formula (I):
- in free or pharmaceutically acceptable salt form, and at least one sildenafil or tadalafil, in free or pharmaceutically acceptable salt form.
Dependencies are inferred from the claim text.