Quinazoline derivatives

Compounds of the formula I

• in which
• A1 denotes N or CR1,
• A2 denotes N or CR2,
• A3, A4,
• A5, A6 each, independently of one another, denote N or CR3,
• X is absent or denotes unbranched or branched alkylene having 1-10 C atoms, in which 1-7 H atoms may be replaced by OH, F and/or Cl,
• and/or in which one or two non-adjacent CH and/or CH2 groups may be replaced by O, N, NH, NA′, CO, S, SO, SO2, OCO, NHCONH, NHCO, NHSO2, COO, CONH and/or CH═CH groups,
• or cycloalkylene having 3-7 C atoms,
• L2 is absent or denotes unbranched or branched alkylene having 1-10 C atoms, in which 1-7 H atoms may be replaced by OH, F and/or Cl,
• and/or in which one or two non-adjacent CH and/or CH2 groups may be replaced by O, N, NH, NA′, CO, S, SO, SO2, OCO, NHCONH, NHCO, NHSO2, COO, CONH and/or CH═CH groups,
• or cycloalkylene having 3-7 C atoms,
• with the proviso that X and L2 cannot be absent simultaneously,
• R denotes H or unbranched or branched alkyl having 1-10 C atoms, in which 1-7 H atoms may be replaced by F and/or Cl and/or in which one or two non-adjacent CH and/or CH2 groups may be replaced by O, N, NH, NA′, CO, S, SO, SO2, OCO, NHCONH, NHCO, NHSO2, COO, CONH and/or CH═CH groups,
• or
• cyclic alkyl having 3-7 C atoms,
• R1 denotes H or unbranched or branched alkyl having 1-10 C atoms, in which 1-7 H atoms may be replaced by F and/or Cl and/or in which one or two non-adjacent CH and/or CH2 groups may be replaced by O, N, NH, NA′, CO, S, SO, SO2, OCO, NHCONH, NHCO, NHSO2, COO, CONH and/or CH═CH groups,
• or
• cyclic alkyl having 3-7 C atoms,
• R2 denotes H or unbranched or branched alkyl having 1-10 C atoms, in which 1-7 H atoms may be replaced by F and/or Cl and/or in which one or two non-adjacent CH and/or CH2 groups may be replaced by O, N, NH, NA′, CO, S, SO, SO2, OCO, NHCONH, NHCO, NHSO2, COO, CONH and/or CH═CH groups,
• or
• cyclic alkyl having 3-7 C atoms,
• R3 denotes H or unbranched or branched alkyl having 1-10 C atoms, in which 1-7 H atoms may be replaced by F and/or Cl and/or in which one or two non-adjacent CH and/or CH2 groups may be replaced by O, N, NH, NA′, CO, S, SO, SO2, OCO, NHCONH, NHCO, NHSO2, COO, CONH and/or CH═CH groups,
• or
• cyclic alkyl having 3-7 C atoms,
• A′ in each case, independently of one another, denotes unbranched or branched alkyl having 1-10 C atoms,
• in which 1-7 H atoms may be replaced by F and/or Cl,
• and/or in which one or two non-adjacent CH and/or CH2 groups may be replaced by O, N, NH, NA, S, SO, SO2 and/or CH═CH groups,
• or
• cyclic alkyl having 3-7 C atoms,
• A denotes alkyl having 1, 2, 3 or 4 C atoms,
• and pharmaceutically usable salts, tautomers and stereoisomers thereof, including mixtures thereof in all ratios.