Novel Heterocyclic Compounds and Uses Thereof

A compound of Formula IV:

• wherein Z1 and Z2 are each independently N or CH;
• where X or Y, whichever is present, is selected from the group consisting of O and S;
• R3 is optionally substituted phenyl, or a C1-C6 hydrocarbyl group;
• R6 is NHR14, where R14 is H or optionally substituted C1-C6 alkyl;
• R7 is H, D, halo, optionally substituted amino or optionally substituted C1-C4 alkoxy;
• and
• R10 is NHR15, wherein R15 is selected from the group consisting of optionally substituted C1-C6 alkyl, optionally substituted heterocyclyl, —C(O)R′, optionally substituted C3-C6 cycloalkyl, optionally substituted amino, optionally substituted aryl, and optionally substituted heteroaryl;
• R′ is H or optionally substituted C1-C4 alkyl;
• or a pharmaceutically acceptable salt thereof.