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US 2013/0210722 A1Published application
Methods for using peptide agonists having glp-1 activity
AssigneeZealand Pharma A/S
InventorsBJARNE DUE LARSEN, JENS DAMSGAARD MIKKELSEN, SØREN NEVE
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Abstract
Novel peptide agonists of GLP-1 activity useful for lowering blood glucose levels. The novel peptides comprise variants of the GLP-1 or the exendin-4 polypeptide sequence and are pharmacologically active and stable. These peptides are useful in the treatment of diseases that benefit from regulation of excess levels of blood glucose and/or regulation of gastric emptying, such as diabetes and eating disorders.
Claims1
A method for treating type 2 diabetes mellitus in a subject in need thereof, said method comprising administering to said subject desPro36-exendin-4(1-39)-Lys6-NH2 (SEQ ID NO:
- 93), or a pharmaceutically acceptable salt thereof in an amount that is effective for the treatment of type 2 diabetes mellitus.
Dependencies are inferred from the claim text.