Nutritional compositions and methods for weaning from parenteral nutrition to enteral nutrition
AssigneeNestec S.A.
InventorsNorman Alan Greenberg, Claudia Roessle
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Abstract
Nutritional compositions and methods of using the nutritional compositions are provided. In a general embodiment, the present disclosure provides a nutritional composition including one or more proteins, one or more amino acids and one or more exogenous nucleotides. The nutritional compositions can be specifically used to assist a patient in weaning from partial or total parenteral nutrition to enteral nutrition with improved tolerance.
Claims22
A nutritional composition comprising a protein, an amino acid and an exogenous nucleotide:
- the protein comprising from about 35% to about 55% of total energy of the nutritional composition and is selected from the group consisting of an intact protein, free amino acids, a whey protein hydrolysate, casein hydrolysate, milk protein hydrolysate, soy protein hydrolysate, pea protein hydrolysate, and combinations thereof;
- the amino acid comprises from about 20 grams to about 40 grams and is selected from the group consisting of a glutamine source, a threonine source, a cysteine source, a serine source, a proline source, and combinations thereof;
- and
- the exogenous nucleotide comprises about 1 to about 4 grams.
A method of making a nutritional composition, the method comprising:
- combining protein, amino acid and endogenous nucleotide in a ratio so that the protein comprises from about 35% to about 55% of total energy of the nutritional composition and is selected from the group consisting of an intact protein, free amino acids, a whey protein hydrolysate, casein hydrolysate, milk protein hydrolysate, soy protein hydrolysate, pea protein hydrolysate, and combinations thereof, the amino acid comprises from about 20 grams to about 40 grams and is selected from the group consisting of a glutamine source, a threonine source, a cysteine source, a serine source, a proline source, and combinations thereof, and the exogenous nucleotide comprises about 1 to about 4 grams to form a nutritional composition.
A method of providing nutrition to a patient, the method comprising:
- providing parental nutrition to a patient;
- and
- administering to the patient having previously received nutrition parenterally a weaning nutritional composition comprising a protein, an amino acid and an exogenous nucleotide, the protein comprising from about 35% to about 55% of total energy of the nutritional composition and is selected from the group consisting of an intact protein, free amino acids, a whey protein hydrolysate, casein hydrolysate, milk protein hydrolysate, soy protein hydrolysate, pea protein hydrolysate, and combinations thereof, the amino acid comprises from about 20 grams to about 40 grams and is selected from the group consisting of a glutamine source, a threonine source, a cysteine source, a serine source, a proline source, and combinations thereof, and the exogenous nucleotide comprises about 1 to about 4 grams.
Dependencies are inferred from the claim text.