Compositions and methods for controlled release of biomolecules
AssigneeCapitalBio Corporation
InventorsSu Guo, Guoqing Wang, Guohao Zhang, Can Wang, Bei Han, Miao Liu, Jinxiu Zhang, Tao Deng, Wanli Xing, Jing Cheng
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Abstract
Provided are compositions for controlled release of biomolecules, which comprise conjugates of polymers and biomolecules conjugated through non-covalent interactions. Also provided are methods for controlled release of biomolecules and their use in biochips.
Claims20
1-52. (canceled)
A controlled release conjugate comprising a biomolecule conjugated with a polymer through a non-covalent bond, which releases the biomolecule from the polymer by a physical treatment and/or change in an environmental condition.
A method for controlled release of a biomolecule comprising:
- a) forming a polymer-biomolecule conjugate by an electrostatic and/or van der Waals interaction;
- and
- b) releasing the biomolecule from the polymer by a physical treatment and/or change in an environmental condition.
Dependencies are inferred from the claim text.