Method and kit for the diagnosis and/or prognosis of tolerance in liver transplantation
AssigneesCentro De Investigacion Biomedica En Red De Enferm Edades Hepatics Y Digestivas, Hospital Clinic De Barcelona
InventorsAlberto Sánchez Fueyo, Juan José Lozano Salvatella, Marc Martínez Llordella, Antoni Rimola Castella, Felix Bohne
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Abstract
The invention refers to a method and kit for the in vitro diagnosis and/or prognosis of the tolerant state of a patient to be submitted to liver transplantation, which comprises assessing the level of systemic and/or intra-hepatic iron stores in a biological sample obtained from the patient under investigation, and comparing it either with the level of iron stores of a reference sample, or with a pre-determined threshold.
Claims18
A method for the in vitro diagnosis and/or prognosis of the tolerant state of a patient subjected to a liver transplantation that comprises:
- a. Obtaining a biological sample from the patient under investigation;
- b. Assessing the level of systemic and/or intra-hepatic iron stores in the sample obtained in step a);
- c. Assessing the tolerance or non-tolerance status of the liver transplant patient under investigation by comparing the level of systemic and/or intra-hepatic iron stores of step b) either with the level of systemic or intra-hepatic iron stores taken from a reference sample, or with a pre-determined threshold.
Dependencies are inferred from the claim text.