Methods and compounds for the diagnosis and treatment of cancer
AssigneeCizzle Biotechnology Limited
InventorDawn Alison Coverley
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Abstract
The present invention provides for methods for use in the diagnosis and prognosis of cancer. The invention further provides to binding agents and kits for us e.g., in such methods. The present invention further relates to compositions, methods of making said compositions and methods of using the same, including use in the treatment and diagnosis of cancer, including lung, lymphoma, liver, thyroid and bladder cancer. Compositions of the present invention useful in the treatment of cancer include anti-sense and small inhibitory RNAs (siRNA).
Claims30
A method of diagnosing cancer in a subject, said method comprising the steps of:
- i) providing an isolated biological sample to be tested;
- ii) detecting whether a Ciz1 b-variant polypeptide is present in said sample,
- wherein the presence of said Ciz1 b-variant polypeptide indicates said subject has cancer.
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An isolated Ciz1 b-variant polypeptide binding agent that specifically binds a Ciz1 b-variant polypeptide.
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A kit for diagnosis and prognosis of cancer in a subject comprising a component for detecting the presence of a Ciz1 polypeptide in a biological sample.
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Dependencies are inferred from the claim text.