Device and method for crystallizing inorganic or organic substances

A device for crystallization of a molecule to be crystallized which comprises:

• at least one crystallization cell, the crystallization cell comprising:
• a crystallization chamber, in which a cavity is made, intended to receiver a first solution S1 containing the molecule to be crystallized and its crystal seeds, and optionally at least one buffer, the cavity including an optical bottom and an aperture facing the optical bottom,
• a dialysis membrane intended to cover the aperture of the cavity of the crystallization chamber,
• a reservoir intended to be fitted onto the crystallization chamber, so as to create a sealed compartment formed by the reservoir on the one hand and by the crystallization chamber on the other hand, the compartment being intended to be filled with a second solution S2, a so-called crystallization solution which contains constituents selected from the group formed by crystallization agents, additives and buffers,
• at least one image acquisition means
• said crystallization device wherein it comprises:
• at least one addition means laid out for adding into the reservoir, constituents selected from the group formed by crystallization agents, additives and buffers to the solution S2 and/or
• at least one sampling means laid out for sampling all or part of the solution S2 in the reservoir.