High troughput multiwell system for culturing 3d tissue constructs in-vitro or in-vivo, method for producing said multiwell sytem and methods for preparing 3d tissue constructs from cells using said multiwell system

A method for producing a multiwell system for use for preparing a 3D tissue construct from cells, comprising steps of:

• a.) melting said biocompatible material in a thermal jacket;
• b.) extruding the melted biocompatible material under pressure through a nozzle to form a plotted fiber;
• c.) step b is repeated, thereby depositing a subsequent plotted fiber in parallel at a distance of between 0.125 and 2.0 mm next to the last deposited fiber until a layer is formed;
• d.) a subsequent layer is deposited on the previous layer, wherein the fibers forming said subsequent layer are deposited at an angle preferably between 10 and 90 degrees relative to the fibers of the previous layer;
• and
• e.) step d is repeated until the desired height is achieved.