Selective drug delivery in a lumen

A medical device, comprising:

• a catheter shaft having a distal region;
• a balloon coupled to the distal region;
• a coating disposed on the balloon, the coating including a releasable drug;
• one or more pairs of bipolar electrodes coupled to the balloon;
• wherein the electrodes are configured to induce a phase change in the coating and release the releasable drug from the coating;
• and
• a generator coupled to the catheter shaft, the generator being configured to selectively energize the electrodes.

A medical device, comprising:

• a catheter shaft having a distal region;
• a balloon coupled to the distal region;
• a thermally changeable coating disposed on the balloon, the coating including a releasable drug;
• wherein the thermally changeable coating has a coating melting temperature above 37° Celsius;
• one or more pairs of bipolar electrodes coupled to the balloon;
• wherein the electrodes are configured to heat the coating above the coating melting temperature so as to at least partially liquefy the coating and release the releasable drug from the coating;
• and
• a generator coupled to the catheter shaft, the generator being configured to selectively energize the electrodes.