US 2013/0172666 A1 · METHOD OF IN VITRO FERTILIZATION WITH DELAY OF EMBRYO TRANSFER AND USE OF PERIPHERAL BLOOD MONONUCLEAR CELLS

Abstract

A method of in vitro fertilization wherein the embryo is implanted into the uterus of a female patient at least two, and preferably three to twelve months after the eggs are retrieved from the patient in order to reduce the effect of autoimmune rejection of the embryo by the patient's autoimmune system and increase the probability and success of pregnancy and wherein prior to embryo implantation, the endometrium in the uterus is prepared for embryo implantation by introducing peripheral blood mononuclear cells (PBMCs) into the uterus. The procedure is combined with cryopreservation techniques to preserve the oocytes or the IVF-produced embryos of the patient.

Claims32

Dependent claims

A method of in vitro fertilization for a female patient, the method comprising the steps of:

(a) introducing into the uterus an effective amount of a composition comprising peripheral blood mononuclear cells, and
(b) transferring at least one embryo into the uterus of the patient after a predetermined delay following initiation of the in vitro fertilization of said patient;
and
wherein the method results in an increase in the probability of implantation of the embryo in the uterus with successful inception of pregnancy when compared to in vitro fertilization methods lacking such steps.

1 more element

Dependencies are inferred from the claim text.

Method of in vitro fertilization with delay of embryo transfer and use of peripheral blood mononuclear cells

Life of this patent

Method of in vitro fertilization with delay of embryo transfer and use of peripheral blood mononuclear cells

Life of this patent

Abstract

Claims32